Volume 7, Issue 4, July 2019, Page: 107-111
Improvement of the Maximum Avoidance of Inbreeding by the Use of Cell Manipulation Technique in Gametogenesis
Takeshi Honda, Food Resources Education and Research Center, Graduate School of Agricultural Science, Kobe University, Hyogo, Japan
Kenji Oyama, Food Resources Education and Research Center, Graduate School of Agricultural Science, Kobe University, Hyogo, Japan
Received: Jul. 24, 2019;       Accepted: Aug. 13, 2019;       Published: Aug. 26, 2019
DOI: 10.11648/j.avs.20190704.14      View  637      Downloads  197
Reduction of genetic drift for preservation of genetic variability is one of the primary concerns for maintenance of endangered species in captivity. For this purpose, a number of selection schemes to equalize parental contributions to the next generation have been widely accepted as a simple guideline, but genetic drift due to random segregation of heterozygote parents, so-called Mendelian sampling, has remained unavoidable. In the past, the use of cell manipulation techniques developed in a field of mammal reproductive technology has been suggested to restrict this genetic drift. However, its potential benefit has been examined only for a randomly mating population of equal sex ratio. In this study, we assumed the situation where the cell manipulation technique is applied to the population under the mating system of maximum avoidance of inbreeding (MAI), and examined its effect on the progress of inbreeding by developing a recurrence equation of panmictic indices of the population. Inbreeding coefficient was substantially suppressed at the locus site where the mean number of crossovers between the site and centromere (m) was small. Although inbreeding coefficient inflated as m increased, its effect diminished as m increased. These tendencies were observed irrespective of the size of the population.
Maximum Avoidance of Inbreeding, Mendelian Sampling, Recurrence Equation, Cell Manipulation Technique, Gametogenesis
To cite this article
Takeshi Honda, Kenji Oyama, Improvement of the Maximum Avoidance of Inbreeding by the Use of Cell Manipulation Technique in Gametogenesis, Animal and Veterinary Sciences. Vol. 7, No. 4, 2019, pp. 107-111. doi: 10.11648/j.avs.20190704.14
Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Frankham, R., Ballou, J. D., and Briscoe, D. A., 2002. Introduction to Conservation Genetics. Cambridge University Press, Cambridge.
Wright, S., 1931. Evolution in Mendelian populations. Genetics 16, 97-159.
Caballero, A., 1994. Developments in the prediction of effective population size. Heredity 73, 657-679.
Wang, J., 2016. Prediction and estimation of effective population size. Heredity 117, 193-206.
Caballero, A., Toro, M. A., 2000. Interrelations between effective population size and other pedigree tools for management of conserved populations. Genet. Res. 75, 331-343.
Fernández, J., Caballero, A., 2001. Accumulation of deleterious mutations and equalization of parental contributions in the conservation of genetic resources. Heredity 86, 480-488.
Gowe, R. S., Robertson, A., Latter, B. D. H., 1959. Environment and poultry breeding problems. 5. The design of poultry control strains. Poult. Sci. 38, 462-471.
Wang, J., 1997. More efficient breeding systems for controlling inbreeding and effective size in animal populations. Heredity 79, 591-599.
Wang, J., Hill, W. G., 2000. Marker assisted selection to increase effective population size by reducing Mendelian segregation variance. Genetics 154, 475-489.
Santiago, E., Caballero, A., 2000. Application of reproduction technologies to the conservation of genetic resources. Conserv. Biol. 14, 1831-1836.
Wakayama, T., Hayashi, Y., Ogura, A., 1997. Participation of the female pronucleus derived from the secondary polar body in full embryonic development of mice. J. Reprod. Fert. 110, 263-266.
Wakayama, T., Yanagimachi, R., 1998. The first polar body can be used for the production of normal offspring in mice. Biol. Reprod. 59, 100-104.
Tesarik, J., Bahceci, M., Özcan, C., Greco, E., and Mendoza, C., 1999. Restoration of fertility by in-vitro spermatogenesis. The Lancet 353, 555-556.
Ogura, A., Suzuki, O., Tanemura, K., Mochida, K., Kobayashi, Y., and Matsuda, J., 1998. Development of normal mice from metaphase I oocytes fertilized with primary spermatocytes. Proc. Natl. Acad. Sci. U. S. A. 95, 5611-5615.
Kimura, M., Crow, J., 1963. On the maximum avoidance of inbreeding. Genet. Res. 4, 399-415.
Robertson, A., 1964. The effect of non-random mating within inbred lines on the rate of inbreeding. Genet. Res. 5, 164-167.
Cockerham, C. C., 1970. Avoidance and rate of inbreeding. In: Kojima, K. (ed), Mathematical Topics in Population Genetics. Springer, New York, pp. 104-127.
Ballou, J. D., Foose, T. J., 1995. Demographic and genetic management of captive populations. In: Kleinman, D. G., Lumpkin, S., Allen, M., Harris, H., Thompson, K. (eds), Wild Mammals in Captivity. University of Chicago Press, Chicago, pp. 263-283.
Ballou, J. D., Lacy, R. C., 1995. Identifying genetically important individuals for management of genetic variation in pedigreed populations. In: Ballou, J. D., Gilpin, M., Foose, T. J. (eds), Population Management for Survival and Recovery, Columbia University Press, New York, pp. 76-111.
Lacy, R. C., 1995. Clarification of genetic terms and their use in the management of captive populations. Zoo Biol. 14, 565-578.
Caballero, A., Toro, M. A., 2002. Analysis of genetic diversity for the management of conserved subdivided poulations. Conserv. Genet. 3, 289-299.
Browse journals by subject